Television series that mix real science and imagery science make up a fascinating genre in popular science. While previous research on entertainment media focuses on Western examples and seldom includes Asian TV series, this study explores how medicine is portrayed in four TV series located in a hospital setting which were broadcasted in Taiwan. Yet, they were produced in different cultures: Taiwan, Japan, South Korea and the United States. We found that the emphasis is more on the social contexts of medicine than on factual medical information. Yet, fictional TV series may be crucial for contextualizing science and science-based medicine.