The problem of accessing data is as old as science itself. Complete popularisation of scientific data (of a theoretical model), and even more so of the methods and materials used during an experimental process and of the empirical data amassed, has always been considered an essential part of the process of authentication, duplication and filing of scientific knowledge. It is also true, however, that this theory has always been a complex riddle with no simple solution. Strangely enough, in today's era of instant communication, the challenge of information access seems to be facing new, daunting obstacles, some of which have the same name and characteristics they had 100 or 300 years ago, but which have been intensified by new dimensions and unexpected corollaries. Others have a new core, an example being, the problem related to disclosure, which implies the (more or less) complete popularisation of the data, procedures, and tools used during research. This is a subject which, although ancient in form, has recently taken on new, far-reaching implications. The scientific community now has to face a problem which originated, first, with the sequencing of the human genome and, later, with that of certain types of rice; a problem which could redefine certain aspects of the epistemological practice and nature of science.

Free information works. In the sense that Open Access Journals, scientific journals which can be accessed at no cost, thereby guaranteeing free access to everyone, are at the same time able to guarantee the same quality as –or even better than- that of traditional journals, which can only be read by those willing to pay a price, be it the cover price or a subscription.

At the beginning of the new millennium, science is not only a neutral system or an objective methodology of knowledge, but also the implicit basis of the totality of our culture. Though science and its derivates are omnipresent in daily life, its basic ideologies and functional mechanisms are in most cases not fully visible to the subject. In using the most evolved systematical-critical model of psychoanalysis provided by the French thinker Jacques Lacan (1901-1981), an enlightening analysis of western science can be made, which contributes not only to a better understanding of its own psychology, but also of the hidden ties between science and its current socio-cultural background.

On September 15, 2001, a joint editorial simultaneously published in thirteen medical journals, pointed an accusing finger at the increasing pressures coming from the pharmaceutical industry. During past decades, a key role in trial design and conduct was played by independent clinical investigators working in academic medical centres. They were also able to vouchsafe the quality of their research, which might not, however, be the case in the future.

On 16 January 2004, the United Nations Secretary-General and Nobel Peace Prize winner Kofi Annan launched a Global Media Aids Initiative, with the aim of convincing the press, radio, television and Internet to join the fight against what has been called the "forgotten disease of the forgotten continent". Throughout the world, over 40 million people have the Hiv virus. In 2003 there were 5 million new infections and 3 million deaths were caused by Aids.

There is a substantial divergence between the standards of integrity associated with "good science" and the problems imposed by the conflict of interest on research, specially in the biomedical field. There are at least as many ways in which information may be altered and the production of new scientific knowledge may be affected as there are links that can be established between researchers, private companies, and editors and staff of the specialized press. The pressures resulting from this high number of connections can affect all stages of research, from trial design to data analysis, from result publishing and dissemination to who will be the author of the articles.