A potential decline in public trust in science has often been linked to digital media environments, which serve as intermediaries of trust by providing cues for why (not) to trust science. This study examines whether exposure to trust cues in content affects public trust in science (across population groups). The study employs a mixed-method design, combining content analysis (“n” = 906) and panel survey data (“n” = 1,030) in Germany. The findings reveal that exposure to trust cues in certain media predicts public trust in science. Variations across trust groups indicate a nuanced nature of trust-assessing processes in digital media environments.