On 15 September 2001, thirteen major international journals, coordinated by the International Committee of Medical Journals Editors (ICMJE), published a joint editorial titled "Sponsorship, authorship, and accountability". Unfortunately, only four days from the tragedy of 9-11, there is no room in the media for other news. In the scientific world, however, the content of that editorial sets off an alarm: the conflict of interest undermines the objectivity of biomedical research and the credibility of international journals vouchsafeing the quality of that research. (Translated by Andrea Cavatorti, Scuola Superiore di Lingue Moderne per Interpreti e Traduttori, Trieste, Italy.)

At the beginning of the new millennium, science is not only a neutral system or an objective methodology of knowledge, but also the implicit basis of the totality of our culture. Though science and its derivates are omnipresent in daily life, its basic ideologies and functional mechanisms are in most cases not fully visible to the subject. In using the most evolved systematical-critical model of psychoanalysis provided by the French thinker Jacques Lacan (1901-1981), an enlightening analysis of western science can be made, which contributes not only to a better understanding of its own psychology, but also of the hidden ties between science and its current socio-cultural background.

There is a substantial divergence between the standards of integrity associated with "good science" and the problems imposed by the conflict of interest on research, specially in the biomedical field. There are at least as many ways in which information may be altered and the production of new scientific knowledge may be affected as there are links that can be established between researchers, private companies, and editors and staff of the specialized press. The pressures resulting from this high number of connections can affect all stages of research, from trial design to data analysis, from result publishing and dissemination to who will be the author of the articles.

On 16 January 2004, the United Nations Secretary-General and Nobel Peace Prize winner Kofi Annan launched a Global Media Aids Initiative, with the aim of convincing the press, radio, television and Internet to join the fight against what has been called the "forgotten disease of the forgotten continent". Throughout the world, over 40 million people have the Hiv virus. In 2003 there were 5 million new infections and 3 million deaths were caused by Aids.

Science was born when knowledge was no longer kept secret and became public. Its development is inextricably tied to the possibility that researchers continue to share the results of their discoveries as easily as possible. These are the points on which the concept of access to scientific information is based and on which the scientific community has founded its model of communication. However, there are currently numerous obstacles, mostly economic, preventing researchers from being real actors in the creation, control and verification process of scientific knowledge. Despite the technologies made available by the Internet, free access to scientific information continues to be limited by the cost of magazines and the opposition by the publishers. Hence, scientists have promoted an increasing number of initiatives with a view to re-confirming the principles of open access.