Responsible Research and Innovation (RRI) is gaining momentum worldwide and is envisaged as a needed tool to properly govern controversial innovative technology (i.e. genome editing, AI). Europe is considered a leader in fostering such approach, notably through its institutionalization. Even so, the future of European Research and Innovation (R&I) seems to be designed without a central role for RRI. After long effort and so much public EU money to support projects to ground RRI principles and practices in key contexts for the flourishing of science and technology in Europe, such as the industrial realm and regional settings, this counter-intuitive decision could undermine the leadership of Europe in prioritizing civil and human rights and needs, values and expectations of its citizens when steering science and technology, that European R&I strongly need to go further.

At the beginning of May, 2018, the European Commission has presented its proposal for Horizon Europe, the framework programme which defines priorities and budget distribution for the future of European Research and Innovation (2021–2027). The announcement has raised concerns within the community of stakeholders engaged in Responsible Research and Innovation (RRI), a democratization process leading to connecting science to the values and interests of European citizens by mean of participatory processes. Through this flash commentary we aim at providing a wide range of arguments, as well as strong examples and concrete suggestions, to the importance of maintaining and strengthening RRI within Horizon Europe, with the hope to inspire amendments to the current proposal.