TikTok has become a popular platform for science communication, particularly among younger audiences, allowing creators to reach broader audiences. However, concerns about the accuracy of science content shared on the platform have emerged, prompting this study to investigate the reliability of informal science communication by popular creators. Informal science communication is the casual sharing of scientific information on platforms like TikTok. The main objective is to assess how well this content adheres to established scientific principles and avoids misinformation. By analysing videos from creators with significant followings, we will evaluate their adherence to scientific accuracy and identify factors that influence it, such as the creators' backgrounds and platform algorithms. The findings will highlight trends in the accuracy of content, with some creators producing reliable information while others risk spreading misinformation. Ultimately, the research will provide recommendations for enhancing the accuracy of science content on TikTok, promoting critical thinking among viewers, and advancing informed science communication on social media.