The Science House of the Federal University of Rio de Janeiro (UFRJ) is a space where science is approached through the perspective of culture, seeking interdisciplinarity, stimulating debate among different areas of knowledge, and building a closer and more pleasant relationship between society and scientific knowledge.  Work with mediators has gone through significant changes over time and the paths chosen have been modified, re-evaluated and transformed.  The presence of mediators can mean the possibility of dialog, conversation, informal chat, and sharing.  It has been one of the main channels of communication with the general public.