In light of global crises such as COVID-19, we argue that people’s trust in science drives their media choices in the digital sphere. The results from a German online survey show that individuals who perceive scientists as trustworthy in terms of ability, benevolence, and integrity, confidently expect science to provide accurate knowledge and guide reasonable decision-making in times of crisis. In turn, these positive trusting expectations towards science increase the use of established journalistic and scientific online sources for accessing scientific information. In contrast, people with low or no trust in science tend to resort to the messenger Telegram and ‘alternative’ online media outlets. Interestingly, the individual need for orientation does not amplify this association between trust in science and digital media use in a crisis situation.