Genetic biocontrol approaches, such as gene drive technology is rapidly gaining interest from scientists and public health professionals due to their potential to overcome many challenges of current malaria control tools and strategies. This is particularly the case in Africa where the burden of malaria is most significant. Uncertainty exists about whether these approaches will work, how effective they might be, who is controlling them, and potential unintended consequences for human health and the environment. Therefore, efforts to enhance the understanding of genetic engineering and biotechnology are needed, to ensure that accurate information about this technology is disseminated in the media by science communicators including the journalists and scientists. In this practice insight, we review the outcomes from workshops and courses hosted by the African Genetic Biocontrol Consortium aimed at equipping communicators and journalists with skilful techniques to proficiently articulate the uncertainties associated with genetic biocontrol interventions to the African public. we discuss the gaps and provide insight on how communicators can address some of the basic challenges of developing effective communication and decision-making for genetic biocontrol approaches in Africa.