What exactly is “scientific culture”? How does it relate to science communication, non-formal education or artistic interactions with the scientific world? That was the topic of the 14th International Summer School of Mind, Brain and Education (ISMBE), held 1–4 October 2019 at the Ettore Majorana Centre for Scientific Culture in Erice (Sicily), Italy. The ISMBE has a long history of bringing together researchers from diverse fields to catalyze research relating to cognitive science and neuroscience through to education, and the directors of the School, Drs. Kurt Fischer, Antonio Battro and Sebastián Lipina considered that the boundary between these fields and scientific culture was subtle enough to demand a conference on the subject and asked us to organize such a meeting.