This is a conference review on PCST 2016 Istanbul. PCST 2016 Conference, with the theme of "Science Communication in Digital Age", was held in Turkey Istanbul on April 26, attracting more than 400 science communication experts and scholars from 52 countries and regions. This conference featured vast topics and rich contents, covering 6 conference reports, 52 sub-forums, 133 oral reports and 52 poster papers focusing on science communication changes, scientists participation, public object, ethics and art, tendency and policy under the background of the digital age.